Synthesis of N-phenylphosphoramidothioic dichloride

GRAPHICAL ABSTRACT

ABSTRACT

N-Phenylphosphoramidothioic dichloride was successfully synthesized from the reaction of thiophosphoryl chloride and phenylamine. Ammonia was used as acid-binding agent in the reaction. The product was fully characterized by IR, NMR (¹H, ¹³C, and ³¹P), and EA. Under the optimized conditions, the overall yield was 85%. There are many advantages for this synthesis method such as simple synthesis procedure, low cost of production, and few by-products.

KEYWORDS:

• N-Phenylphosphoramidothioic dichloride
• acid-binding agent
• organophosphorus
• thiophosphoryl chloride

Funding

We are grateful to the National Science and Technology Support Program [2014BAB15B02].