Synthesis, characterization and antimicrobial activity of β-aminovinylphosphonium salts derived from aromatic amino acids

GRAPHICAL ABSTRACT

ABSTRACT

This study presents the synthesis, characterization and antimicrobial activity evaluation of β-aminovinyl-phosphonium salts derived from aromatic amino acids. The compounds were prepared in the reaction of (formylmethyl)triphenylphosphonium chloride with various aromatic amino acids and their structures were determined by elemental analysis, IR and NMR spectroscopy. All synthesized compounds were tested for their antibacterial and antifungal activity.

KEYWORDS:

• β-Aminovinylphosphonium salts
• aromatic amino acids

Funding

The research is supported by the RA MES SCS, within the frames of the “RA MES SCS – YSU-RF SFEDU” internal call for joint project VnGr-07/2017-35, Ministry of Education, Science and Technological development of the Republic of Serbia (Grant OI 172055) and taking advantage of the facilities of Resource Centers of SFEDU “Molecular spectroscopy.”