Chromium(III) complexes of dimethyl diphenyldithiophosphates: Synthesis, characterization, and antibacterial studies

GRAPHICAL ABSTRACT

ABSTRACT

Dimethyl diphenyldithiophosphate complexes of Cr(III), [{(ArO)₂PS₂}₃Cr] [Ar = 2,4-(CH₃)₂C₆H₃ (1), 2,5-(CH₃)₂C₆H₃ (2),3,4-(CH₃)₂C₆H₃ (3), and 3,5-(CH₃)₂C₆H₃ (4)], have been synthesized and structurally characterized by IR, heteronuclear NMR (¹H, ¹³C, and ³¹P) spectroscopic and single crystal X-ray analyses. The crystal structure of complex 4 reveals mononuclear units with the Cr(III) centre chelated in bidentate fashion by six S atoms of the three diphenyldithiophosphate ligands to form octahedral geometry. The main core of the system comprised of four membered (CrS₂P)₃ heteroatomic ring and Cr(III) center. The ligands and complexes were evaluated for their antibacterial potential against six bacterial strains (K. pneumoniae, E.coli, P. aeruginosa, B. subtilis, S. aureus, and S. typhimurium). The metal derivatives of diphenyldithiophosphate ligands were found to be more active against the bacterial strains as compared to the free ligands.

KEYWORDS:

• Diphenyldithiophosphate
• single crystal X-ray
• octahedral geometry

Acknowledgments

The authors are grateful to the NMR laboratory, Department of Chemistry, University of Jammu, Jammu for providing NMR spectral facilities (PURSE program). One of the authors (Rajni Kant) acknowledges the DST for the single crystal X-ray diffractometer as a National Facility under Project No. SR/S2/CMP-47/2003.