Crystal structure, antibacterial activity and nanoparticles of Cd(II) complex derived from dithiophosphonate ligand

GRAPHICAL ABSTRACT

ABSTRACT

The binuclear complex of the type Cd₂(HL)₄ was isolated from the reaction of cadmium(II) nitrate and dithiophosphonate ligands of the type R₁R₂PSSH (R₁ = CH₃OC₆H₄ and R₂ = (CH₃)₂CHCH₂CH₂O). The crystal structure of bis-{bis-[O-3-methylbutyl (4-methoxyphenyl) dithiophosphonato] cadmium(II)}, Cd₂(HL)₄, has been determined by means of single-crystal X-ray diffraction methods. The cadmium is tetra-coordinated structure and constitutes a nearly planar geometry with the atoms on the PS₂ group of the ligand. The nanoparticles of the complex were also prepared by ultrasonication, and their SEM micrographs indicated identical spherical morphologies with particles sizes about 32–39 nm. The complex and ligand were additionally tested in view of their antibacterial properties. The cadmium(II) dithiophosphonato complex was found to be more active against E. coli and S. aureus than free ligand.

KEYWORDS:

• antibacterial activity
• Cd(II) complex
• dithiophosphonate
• nanoparticles
• Ultrasonication
• X-ray crystallography

Acknowledgements

We are grateful to University of Ardabil Payamenoor and Islamic Azad Germi University for supporting this research. PMc thanks NUI Galway University for support of the NUI Galway Crystallography Laboratory.