Herbicidal activity and application cyclic of phosphonates

Abstract

Among alkylphosphonates Io, O,O-dimethyl 1-(2,4-dichlorophenoxyacetoxy) ethylphosphonate (clacyfos) was found to be an effective inhibitor against dicotyledons PHDc and exhibited excellent herbicidal activity in our previous work. According to our study on the alkylphosphonates Io, both R¹ and R² groups in the structural unit of phosphorus-containing played a very important role in herbicidal activity. Therefore, a series of 2-[1-(substituted phenoxycarboxy)alkyl]-5,5-dimethyl-1,3,2-dioxaphosphinane-2-one containing fluorine II was obtained by the modification of alkylphosphonates Io. The bioassay results showed that cyclic phosphonate II-6 with CH₃ as R_, 2-Cl,4-F as Y_n exhibited promising herbicidal activity. Its herbicidal activity, weed-controlling spectrum, selectivity between crops and weeds were further evaluated in greenhouse and field.

Graphical Abstract

Keywords:

• Cyclic alkylphosphonate
• herbicidal activity
• fluorine

Additional information

Funding

The work was supported in part by the National Research and Development Plan (2017YFD0200506), the National Natural Science Foundation of China (21877047), 111 Project B17019.