Abstract
An highly efficient and environmentally friendly process for the synthesis of α-aminophosphonates has been devised, through a one-pot three-component condensation of various aldehydes, amines and triethyl phosphate in water-ethyl lactate under ultrasonic irradiation conditions at room temperature. The expected products were obtained in high yield without the need for any additional catalyst.
Graphical Abstract
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Disclosure statement
No potential conflict of interest was reported by the authors.