Comparison of catalytic activity of hexamethyltriamino- and tri-n-butylphosphines in the Pudovik reaction

Abstract

The catalytic activity of hexamethyltriaminophosphine in the P(O)–H bond addition to electron-deficient alkenes was studied. Depending on the nature of the alkene, hexamethyltriaminophosphine produces better or lower yields of the reaction products compared to tri-n-butylphosphine.

Graphical Abstract

Keywords:

• Tertiary phosphines
• Pudovik reaction
• organocatalysis
• electron-deficient alkenes
• α-effect