Abstract
Efficient palladium catalyst systems based on the combination of bench stable biaryl phosphacycles and Pd(OAc)2 are described for Suzuki-Miyaura cross-coupling reactions of aryl bromides and chlorides. Notably, the electronically and sterically diametric biaryl phosphacycles allowed facile coupling of sterically hindered and heterocyclic substrates.
Graphical Abstract
Acknowledgments
We are thankful for financial support from Research Centre for Synthesis and Catalysis (UJ) and Sasol. The authors also thank Sasol for providing secondary phosphines phobane-H and Cg-H.