2,6-Dicarboxypyridinium Fluorochromate: A Mild and Efficient Reagent for Oxidative Deprotection of Trimethylsilyl Ethers to Their Corresponding Carbonyl Compounds

Deprotection of trimethylsilyl ethers to their parent aldehydes and ketones in high yields has been carried out using 2,6-dicarboxypyridinium fluorochromate under mild conditions.

Keywords:

• 2,6-Dicarboxypyridinium fluorochromate
• deprotection
• oxidative
• trimethylsilyl ethers

Notes

^a Yields refer to isolated products.

^a All of the products were characterized by comparing them with known compounds and their IR and ¹H NMR showed physical and spectral data in accordance with their expected structure and with authentic samples.

^b Yields refer to isolated products.

^a 2,6-Dicarboxypyridinium fluorochromate.

^b Quinolinium fluorochromate.

^cBenzyltriphenylphosphonium chlorate.

^d Room temperature.