Some bromo- and chloromethyl pyridines were synthesized using radical substitution reactions. Further reaction of these halopyridines with activated tetrabutylammonium fluoride under mild conditions gave the related fluorinated pyridines. The yields of products following recrystallization were of the order of 30–93%. 1 H, 13 C, and 19 F spectroscopies together with elemental analysis were used characterize products.
Synthesis of Some Fluorinated Pyridines Using Tetrabutylammonium Fluoride
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