Abstract
The reaction of phosphono-immoniumchloride 5 with phosphinites 6 gives a 1:1 mixture of the diastereomeres of dimethylaminomethyl-phosphonates-phosphinites 7. Modest diastereoselectivity is observed in the addition to 7-phosphorylated quinonemethides 10 of ethyl methylphosphonite 11. The size of the P-substituent exerts a small effect on the diastereoselectivity of P–C bond formation.