Abstract
The reaction of 4-phenyl-3-thiosemicarbazide derivatives 1a-e with 3-aminoacetonitrile (2) gave the condensed products 3a-e. The reactivity of the latter products toward variety of chemical reagents was studied. Moreover, the reaction of 3b with phenylisothiocyanate; followed by cyclization with α-haloketones 6, 7 and 16, gave the thiazole and thiophene derivatives.