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Leukemia & Lymphoma Volume 58, 2017 - Issue 3
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Letters to the Editor

A common ancestral DNMT3A-mutated preleukemic clone giving rise to AML and MDS in an adolescent girl

Gudrun GöhringInstitute of Human Genetics, Hannover Medical School, Hannover, Germany; Correspondence[email protected]
,
Kathrin ThomayInstitute of Human Genetics, Hannover Medical School, Hannover, Germany;
,
Gunnar SchmidtInstitute of Human Genetics, Hannover Medical School, Hannover, Germany;
,
Tim RippergerInstitute of Human Genetics, Hannover Medical School, Hannover, Germany;
,
Michael XuInstitute of Human Genetics, Hannover Medical School, Hannover, Germany; ;Manitoba Institute of Cell Biology, CancerCare Manitoba, Winnipeg, Canada;
,
Nicole WittnerInstitute of Human Genetics, Hannover Medical School, Hannover, Germany;
,
Mwe Mwe ChaoDepartment of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany;
,
Irith BaumannDepartment of Pathology, Clinical Center, Böblingen, Germany;
,
Marena NiewischDivision of Pediatric Hematology and Oncology, Department of Pediatrics, University Medical Center Freiburg, Freiburg, Germany;
,
Dirk ReinhardtClinic for Pediatrics III, University Hospital Essen, Essen, Germany;
,
Thomas KlingebielHospital for Children and Adolescents, University Hospital Frankfurt, Frankfurt, Germany;
,
Felicitas TholDepartment of Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany
,
Brigitte SchlegelbergerInstitute of Human Genetics, Hannover Medical School, Hannover, Germany;
&
Charlotte M. NiemeyerDivision of Pediatric Hematology and Oncology, Department of Pediatrics, University Medical Center Freiburg, Freiburg, Germany;
show all
Pages 718-721 | Received 10 Jun 2016, Accepted 22 Jun 2016, Published online: 28 Nov 2016
 
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Potential conflict of interest

Disclosure forms provided by the authors are available with the full text of this article online at http://dx.doi.org/10.1080/10428194.2016.1207765.

Funding

This work was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) for the Cluster of Excellence REBIRTH (From Regenerative Biology to Reconstructive Therapy) [EXC 62/3] and the Deutsche Krebshilfe [MDS Verbund 110299 and Verbund 109714].

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