BCR-ABL1 co-occurring with CBFA2T3-GLIS2 and RAM immunophenotype in a non-Down syndrome infant with acute megakaryoblastic leukemia

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Acknowledgments

The authors acknowledge with gratitude Dr. Marcelo Land, Dr. Renata Binato, and Moisés Rocha. We thank Drs. Soheil Meshinchi and Michael Loken for their invaluable suggestions and Alice Theophilo Teixeira de Matos Bch. for editing the figures. This work was dedicated to the Brazilian indigenist Bruno Pereira in memoriam.

Authors’ contributions

Capela de Matos RR, Silva MLM, and Ribeiro RC participated in the design of the study and manuscript writing; Rouxinol M performed the clinical history of the patient; Capela de Matos RR and Silva MLM conducted the conventional cytogenetic analyses and performed FISH; Costa ES and Mello FV performed and revised the immunophenotypic studies; Ferreira GM and Zalcberg I performed the NGS studies; Bonecker S performed the RT-PCR, RT-qPCR analyses, and literature review; Capela de Matos RR, and Ferreira GM participated in the manuscript editing; Silva MLM, Zalcberg I, Abdelhay E, and Ribeiro RC revised the manuscript critically for important intellectual content.

Disclosure statement

The authors report there are no competing interests to declare.

Additional information

Funding

This work was supported by FAPERJ (project no. E-26/210.419/2019, 248798), Brazil; the Ministry of Health (MS), Brazil; the National Cancer Control Program INCA, Brazil.