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Abstract
Gas chromatography mass spectroscopy (GCMS) analysis of unsaponifiable matters of aerial parts of Dichrostachys cinerea revealed the identification of 34 compounds representing 93.67% of the total peak area. The main compounds were isophytol (25.43%), butylated hydroxyl toluene (15.08%), octadecene (8.57%), hexdecene (8.51%), 5-eicosene (6.86%), 3-tetradecene (4.30%), p.nonyl phenol (4.13%), 1-eicosanol (3.41%), and teracosene (2.74%). Thirty-one compounds representing 92.08% of the total peak area were identified by GCMS analysis of fatty acid methyl esters, the main compounds were methyl 9,12,15 octadecatrienoate (25.55%), methyl-12-hydroxy-9-octadecenoate (22.43%), methyl octadecanoate (6.31%), and methyl tetracosanoate (3.83%). Unsaturated fatty acids constituted 53.63% while saturated fatty acids constituted 38.45%. Analgesic and antipyretic activity of the total ethanol extract and successive extracts showed highest activities after 2 h by100 mg of total ethanol extract (80.87% potency) comparable to metamizol and the methanol extract (121.76% potency) comparable to paracetamol.