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Articles

Ononis natrix and Salvia verbenaca: Two Jordanian Medicinal Plants with Cytotoxic and Antibacterial Activities

Pages 18-25 | Received 24 May 2016, Published online: 04 Nov 2016
 

ABSTRACT

The phytochemical constituents and antibacterial and cytotoxic activities of Ononis natrix and Salvia verbenaca were appraised. Ethyl acetate extracts of these plants tested positive for flavonoids and terpenes and negative for alkaloids. The extracts inhibited growth of the gram-positive Bacillus subtilis and B. brevis (MIC 12.5–50 µg.mL–1) and were cytotoxic to the MDA MB-231 breast cancer cell line (IC50 29–41 µg.mL–1).

Acknowledgments

The author would like to thank Dr. Erkel, University of Kaiserslautern, Germany, for the space availability in his laboratory to perform the cytotoxicity assay.

Funding

This work was carried out during a scientific trip funded by the German Research Foundation (DFG) (Grant ER176/8-1).

Additional information

Funding

This work was carried out during a scientific trip funded by the German Research Foundation (DFG) (Grant ER176/8-1).

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