ABSTRACT
The phytochemical constituents and antibacterial and cytotoxic activities of Ononis natrix and Salvia verbenaca were appraised. Ethyl acetate extracts of these plants tested positive for flavonoids and terpenes and negative for alkaloids. The extracts inhibited growth of the gram-positive Bacillus subtilis and B. brevis (MIC 12.5–50 µg.mL–1) and were cytotoxic to the MDA MB-231 breast cancer cell line (IC50 29–41 µg.mL–1).
Acknowledgments
The author would like to thank Dr. Erkel, University of Kaiserslautern, Germany, for the space availability in his laboratory to perform the cytotoxicity assay.
Funding
This work was carried out during a scientific trip funded by the German Research Foundation (DFG) (Grant ER176/8-1).