Antioxidant and Antimicrobial Potential of Costus Woodsonii

ABSTRACT

The antioxidant and antimicrobial activity of the methanolic extracts of various plant parts of Costus woodsonii were evaluated. The total phenolic content and total flavonoid content in leaves and inflorescence extracts were higher compared to the rhizome and stem extracts. Highest total tannin content was noted in the inflorescence. Leaves extracts demonstrated the strongest 2,2-diphenyl-1-picrylhydrazyl scavenging and ferric reducing power activity (IC₅₀ = 1.3 ± 0.2 mg mL⁻¹; FRP = 3.8 ± 0.5 mg mL⁻¹). Rhizome extract showed ferrous ion chelating activity with CC₅₀ at 2.7 ± 0.3 mg mL⁻¹. The leaves extract demonstrated antimicrobial activities against various Staphylococcus aureus strains (MIC: 0.625 mg mL⁻¹ and 1.25 mg mL⁻¹). Liquid chromatography-mass spectrometry (LCMS-MS) analysis showed that rutin and quercetin-3-galactoside were found in leaves; epicatechin in the inflorescences; and dioscin in the rhizomes.

KEYWORDS:

• Phytochemical screening

Acknowledgments

The project was conducted at Monash University Malaysia. The authors thank the Public Service Department Malaysia, Monash University Malaysia and TORAY for the financial support.

Conflict of Interest

The authors have no conflict of interest to declare.

Additional information

Funding

This work was supported by the Toray Foundation (Malaysia); Public Service Department, Malaysia.