ABSTRACT
Antimicrobial activity of solvent extracts of Brassica nigra, Trigonella foenum-graecum, and Schinus molle were investigated against six bacterial pathogens. The highest zone of inhibition (ZOI) were noted for methanol extract of B. nigra against S. boydii. The highest activity index (AI) was noted in methanol extract of B. nigra against S. boydi (AI = 0.86) using ciprofloxacin as positive control but AI ≥ 1.0 in some extracts while using gentamicin as positive control. The minimum inhibitory concentration (MIC) of the extracts ranged from 6.25 mg mL−1 to 100 mg mL−1. The antibacterial activity of the extracts was B. nigra > T. foenum-graecum > S. molle.
Acknowledgments
We thank the Department of Biology, the College of Natural and Computational Sciences, and the School of Graduate Studies of Madda Walabu University for their administrative and material support. We are also highly grateful to the Ethiopian Public Health Institute for providing us the bacterial test pathogens used in this study. The National Herbarium in Addis Ababa (Ethiopia) is also acknowledged for its cooperation in the identification of plant samples used in this study. We also thank Ann Byers for editing the manuscript at short notice.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Data availability statement
All relevant data are within the manuscript and its supporting information files.
Supplementary material
Supplemental data for this article can be accessed online at https://doi.org/10.1080/10496475.2023.2269372