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Natural Product Research
Formerly Natural Product Letters
Volume 18, 2004 - Issue 2
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Original Articles

Two new norsesquiterpenes from Ligularia Lapathifolia

Yun-Sen Li Department of Pharmacognosy, China Pharmaceutical University, Nangjing 210038, P. R. China
,
Zheng-Tao Wang Department of Pharmacognosy, China Pharmaceutical University, Nangjing 210038, P. R. China
,
Mian Zhang Department of Pharmacognosy, China Pharmaceutical University, Nangjing 210038, P. R. China
,
Ji-Jun Chen Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
&
Shi-De Luo Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
Pages 99-104 | Received 20 Dec 2002, Accepted 04 Apr 2003, Published online: 15 Aug 2006
 
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Abstract

Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy)-6-oxo-1,2,3,4,4a,5,6,8a-octahydro-naphthalene-1-carboxylic acid (2), respectively, on the basis of spectral data and for 1 by single-crystal X-ray analysis.

Acknowledgement

This research was financially supported by the Natural Science Foundation (NSFC) for outstanding young scientists, for Wang Z.T. (39825129).

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