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Integrated Ferroelectrics
An International Journal
Volume 131, 2011 - Issue 1
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Original Articles

Multifunctionality of Perovskites BaTiO3 and CaTiO3 in a Composite with Hydroxyapatite as Orthopedic Implant Materials

A. K. Dubey Laboratory for Biomaterials, Department of Materials Science and Engineering, Indian Institute of Technology, Kanpur-208016, UP, India
,
B. Basu Laboratory for Biomaterials, Department of Materials Science and Engineering, Indian Institute of Technology, Kanpur-208016, UP, India
,
K. Balani Laboratory for Biomaterials, Department of Materials Science and Engineering, Indian Institute of Technology, Kanpur-208016, UP, India
,
R. Guo MeMDRL, Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, TX-78249, USA
&
A. S. Bhalla MeMDRL, Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, TX-78249, USA
Pages 119-126 | Received 15 Feb 2011, Published online: 16 Dec 2011
 
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Abstract

In the present article, the multifunctional behavior of perovskites BaTiO3 and CaTiO3 has been studied for their potential orthopedic applications. The biocompatibility and electrical conductivity properties of HA-40 wt%BaTiO3 (25.9 vol% BaTiO3) and HA-40 wt% CaTiO3 (35.3 wt% CaTiO3) composites were investigated to verify its suitability as hard tissue replacement materials. L929 mouse fibroblasts and Human osteoblasts (SaOS2) cells were used to study the cell adhesion and proliferation behavior on the composite surfaces. It has been observed that the developed composites are biocompatible and the conductivity and dielectric behavior of the composite is comparable to dry human bone.

Acknowledgments

We wish to acknowledge the financial support provided by the Indo-US Joint Center on Biomaterials for Health Care and National Science Foundation (grant/0844081).

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