ABSTRACT
“Selective etching based on structural differences” strategy to produce hollow nanosilica (sSiO2@mSiO2), which is different from the traditional composition of the core by using structural differences rather than the silica core or mesoporous silica Shell structure to create hollow interior. We synthesized highly dispersed hollow mesoporous silica spheres with unetched sSiO2 inside, which showed high loading capacity of the anticancer drug (doxorubicin).
5. Funding
This work is financially supported by the National Natural Science Foundation of China (21375069, 21574072, 21675091, 21404065), the Natural Science Foundation for Distinguished Young Scientists of Shandong Province (JQ201403), the Taishan Young Scholar Program of Shandong Province (tsqn20161027), the Key Research and Development Project of Shandong Province (2016GGX102028, 2016GGX102039), the Project of Shandong Province Higher Educational Science and Technology Program (J15LC20), the Scientific Research Foundation for the Returned Overseas Chinese Scholars of State Education Ministry (20111568), the People's Livelihood Science and Technology Project of Qingdao (166257nsh), and the Postdoctoral Scientific Research Foundation of Qingdao.