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Research Article

Synthesis and Photothermal Application of D-A-D Conjugated Small Molecular Nanoparticles

, , , , , & show all
Pages 47-52 | Received 18 Jun 2020, Accepted 15 Feb 2021, Published online: 24 Jun 2021
 

Abstract

The conjugated compound (3Z,6Z)-3,6-bis((5-(9,9-bis(2-octyldodecyl)-9H-fluoren-2-yl) thiophene-2-yl) methylene) piperazin-2,5-dione(p-QM2AF) was synthesized successfully. Nanoparticles (NPs) coated with p-QM2AF compound were prepared from liposomes. The morphology of NPs was characterized by transmission electron microscope and dynamic light scattering instrument, and the NPs maintained high stability after long time storage. Cytotoxicity test was used to evaluate the safety of nanoparticles, and the photothermal properties were characterized.

Additional information

Funding

This work is financially supported by the National Natural Science Foundation of China (21874078, 22074072), the Taishan Young Scholar Program of Shandong Province (tsqn20161027), the Major Science and Technology Innovation Project of Shandong Province (2018CXGC1407), the Key Research and Development Project of Shandong Province (2016GGX102028, 2016GGX102039, 2017GGX20111), and the First Class Discipline Project of Shandong Province.

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