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Articles

Supramolecular catalysis in the synthesis of polyfunctionalised pyrroles

, , , , , , & show all
Pages 882-889 | Received 22 Jul 2013, Accepted 16 Dec 2013, Published online: 24 Mar 2014
 

Abstract

An efficient sequential one pot three component reaction involving anilines, DEAD/DMAD and glyoxal in aqueous media is reported. The protocol is environmentally benign and provides a new synthetic route to access polyfunctionalised pyrrole derivatives in high yield. The reaction proceeded via supramolecular catalysis.

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