340
Views
8
CrossRef citations to date
0
Altmetric
Review Articles

Biointerface: a nano-modulated way for biological transportation

&
Pages 456-467 | Received 10 Sep 2019, Accepted 19 Jan 2020, Published online: 03 Feb 2020
 

Abstract

The concept of biointerface emerges in the fields of biochemistry, genomics, cellular biology and life science. The integration of nanoparticles and biointerfaces creates the scope in different areas like biology, biochemistry, biotechnology and microbiology. The mode of action of nanoparticles through biointerface involves the formation of the protein corona, cellular contact, endocytosis and intracellular transport. The article highlights the complexation of host-guest and types of biointerfaces based on the principles of light, pH, redox reaction and competitive binding. Three major theories include Arrhenius theory, interfacial theory and electron theory. Apart from electron transfer, polymer complexation and kinetic drug release, the energy of activation play an important role in the formation of biointerface. The applications of nano-biointerface include cell patterning, gene delivery, blood-contacting device and cancer therapy. The review article focuses on the potential of biointerface in nano-based systems due to longer contact time, higher surface area, better drug loading efficiency and adhesion for increasing lift-off force, cell penetration, drug delivery of nanocarriers and on-targeting effect to the infected cells. Further, advancement in this field will increase the efficiency of gaseous systems like nanobubbles, nanodroplets, nanoshells, nanocages and nanopopcorn.

Disclosure statement

The authors declare no potential conflict of interest.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 767.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.