Self-assembled bioconjugates for biochip technologies

Abstract

This article gives an overview on current research in the area of self-assembled bioconjugates comprised of DNA-, protein- and nanoparticle building blocks. In particular, the highly specific molecular recognition capabilities of short DNA oligomers are utilized to organize inorganic nanoparticles and proteins, thereby allowing for the fabrication of functional biomolecular hybrid devices. These devices are employed, for instance, to generate programmable biomaterials and probes for bioanalytical methods, such as immunological assays and microarray technologies.

Keywords:

• Bioconjugates
• DNA
• Proteins
• Microarrays
• Self-assembly

Notes

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Additional information

Notes on contributors

Christof M. Niemeyer *

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