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Hypertension in Pregnancy Volume 26, 2007 - Issue 3
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Original

Familial Occurrence of Gestational Hypertensive Disorders in a Brazilian Population

F. M. Araujo Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, BrazilCorrespondence[email protected]
,
G. Duarte Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
,
J. Nomelini Department of Genetics, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
,
R. B. Lôbo Department of Genetics, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
&
E. S. Ramos Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil; Department of Genetics, University Hospital of Medicine School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil
Pages 357-362 | Published online: 07 Jul 2009
 
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Abstract

Objective: To verify the occurrence of preeclampsia/eclampsia (PE/E) or gestational hypertension (GH) in first-degree relatives of Brazilian pregnant women. Methods: A total of 485 women were enrolled in the study, and 226 were selected (75 with PE/E, 49 with GH, and 102 women with normal pregnancies). Statistical analysis was performed using Fisher's exact test. Results: The frequency of families with mothers and/or sisters with PE/E was higher among the PE/E group compared to the GH and the control groups, and was statistically significant (p < 0.05). Conclusion: Women with PE/E have more female first-degree relatives with PE/E as observed in a Brazilian population.

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