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Abstract
Environmental pollution is a growing public health concern worldwide and adverse pollutants are associated with a variety of cancers. microRNAs (miRNAs), a class of small non-coding RNAs, act as powerful and sensitive posttranscriptional regulators of gene expression. Recent reports demonstrate that miRNAs play important roles in apoptosis and senescence, both of which are regarded as protective mechanisms against the carcinogenesis. Here, we will give an overview on the expression profile and regulatory role of miRNA in response to environmental pollution. This review will provide better understanding of the potential of miRNAs as novel biomarkers and therapeutic targets for human cancers caused by environmental pollutants.