Improved Large Scale Purification Procedure of Natural Human Fibroblast Interferon

W. E. Dembinski Department of Biological Resources and Cellular Biology, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, New York, 14263

E. Sulkowski Department of Biological Resources and Cellular Biology, Roswell Park Memorial Institute, 666 Elm Street, Buffalo, New York, 14263

Abstract

Human fibroblast interferon, produced in tissue culture by a super induction procedure, was purified 10,000-fold by chromatography to ca 50% purity as judged by SDS-PAGE. The specific activity of the interferon preparation is 2×10⁸ and the yield is 70%. The interferon preparation is suitable for clinical use.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Improved Large Scale Purification Procedure of Natural Human Fibroblast Interferon

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Improved Large Scale Purification Procedure of Natural Human Fibroblast Interferon

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date