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Original Articles

Microchip Affinity Capillary Electrophoresis: Applications and Recent Advances

, &
Pages 1047-1076 | Received 01 Sep 2005, Accepted 14 Dec 2005, Published online: 06 Feb 2007
 

Abstract

This review gives the basic principle of affinity capillary electrophoresis (ACE) and examines its utilization in bioscience on microchips. ACE on chip is used as a separation tool as well as for study of molecular interactions. MEKC and chiral separations on microfluidic systems are described. Applications for measuring bioaffinity are focused on enzyme assay and immunoassay that demonstrate a further development of classical ACE in capillaries.

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