Rapid and Accurate Determination of Dichlorvos in Water by Liquid Chromatography‐Electrospray Ionization‐Tandem Mass Spectrometry

Abstract

An LC‐MS/MS method has been developed and validated for the determination of dichlorvos in ground and surface waters. The aqueous samples (20.0 mL) are led through a silica‐based C₈+WAX mixed‐mode SPE cartridges. Such a step successfully eliminates humic substances and other interferences that induce a matrix effect. Since the recovery of dichlorvos is 100% and the matrix effect is eliminated, the calibration standards prepared in DI water can be used for accurate and rapid determination of dichlorvos in various aqueous samples. The quantification limit is 0.01 µg/L.

Keywords:

• Dichlorvos
• LC‐MS/MS
• Matrix effect
• C8+WAX mixed‐mode

Acknowledgment

This study was funded in part by the National Science Foundation of China (30470277), Gansu National Science Foundation (3ZS061‐A25‐070) and Gansu Key Technologies R&D Program (ZGS052‐A41‐0006‐03). The content of the work reflects the personal view of the author and not necessarily the view of the organization.