SURFACE MODIFICATION OF SILICA-BASED MONOLITH WITH POLY(PENTAFLUOROPROPYL METHACRYLATE) USING SINGLE STEP PHOTOGRAFTING

Abstract

Photografting has been utilized to achieve on-column functionalization of porous silica monoliths in capillaries. The pore surface was first modified with 3-((trimethoxysilyl)propyl) methacrylate (γ-MAPS) and then photografted in a single step with poly(pentafluoropropyl methacrylate) (PFM). The chromatographic performance of these grafted capillary columns was evaluated using reversed-phase separation of alkylbenzenes.

Keywords:

• alkylbenzenes
• capillary column
• monolith
• pentafluoropropyl methacrylate
• photografting
• silica

ACKNOWLEDGEMENTS

Experimental work carried out at the Molecular Foundry, Lawrence Berkeley National Laboratory was supported by the Office of Science, Office of Basic Energy Sciences of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Joao Luna and Zuzana Zajickova were supported by the Department of Energy (DOE)/National Science Foundation (NSF) Faculty and Student Team (FaST) Program. Joao Luna was supported by NIH-NIGMS MARC U*STAR grant T34 GM008021. Jana Krenkova from the Molecular Foundry is kindly acknowledged for her valuable suggestions helping implementation of this project.