Abstract
Flumequine is a fluoroquinolone antibiotic, mainly used in veterinary and, to some extent, in human treatment. It can be found as a residue in milk and in other food products. A new version of matrix solid-phase dispersion of milk samples spiked with this antibiotic was developed. This preseparation method was combined with thin-layer chromatography–direct bioautography to obtain semi-quantitative results. Escherichia coli were used as test bacteria. The various modes of the procedure were tested, and the one giving the best recovery of the antibiotics from milk was chosen.
Notes
The results related to chromatograms described as Figures and .