Detection Dicyandiamide in Environmental Water by Liquid Chromatography–Mass Spectrometry Combined with Solid Phase Extraction Method

Abstract

A new analytical method has been developed to determine dicyandiamide in environmental water. Residues of dicyandiamide were extracted from the environmental water samples by solid phase extraction using Waters Sep-Pak AC2 Cartridge. The extraction procedure condition (included loading, washing, and eluting) of flow rate of 1.0 mL/min, and dicyandiamide was eluted with 20 mL of acetonitrile and methanol (v/v = 60:40) mixture solution, and preconcentrated using nitrogen evaporation followed by analysis with liquid chromatography–mass spectrometry. Laboratory method validation data was collected in water samples at concentration down to 1.0 ng/mL. Average recovery and relative standard deviation using spiked calibration standard curve were 89% and 2.9%, respectively. The method provides a effective approach to monitor the contaminant in environmental water samples.

Keywords:

• analytical method
• dicyandiamide
• environmental water
• liquid chromatography-mass spectrometry
• solid phase extraction
• trace analysis

Notes

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