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Original Articles

Use of Native and Chemically Modified Cyclodextrins for the Capillary Electrophoretic Separation of Enantiomers

, &
Pages 1023-1040 | Published online: 23 Sep 2006
 

Abstract

Capillary zone electrophoresis is shown to be useful for the separation of select enantiomers via the use of mobile phases containing cyclodextrins (CDs). Both native and chemically modified CDs are utilized herein. Parameters important in achieving enantiomeric separations are CD type, concentration, and mobile phase pH. In addition, rapid (1 minute) enantiomeric separations are demonstrated. Experimental parameters important in attaining short analysis times are discussed.

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