Iohexol Determination by Direct Injection of Serum on the HPLC Column

Z. K. Shihabi Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, 27157-1072

E. N. Thompson Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, 27157-1072

M. S. Constantinescu Department of Medicine (cardiology), Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, 27157-1072

Abstract

Iohexol, a non-ionic compound used as a contrast media for angiography and as a mesure to determine glomerular filtration rate, was measured in serum by injecting serum directly on the column after a 200 fold dilution. The analysis was accomplished in less than 5 min.

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Iohexol Determination by Direct Injection of Serum on the HPLC Column

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Iohexol Determination by Direct Injection of Serum on the HPLC Column

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