Pharmaceutical implants: classification, limitations and therapeutic applications

Abstract

Controlled/sustained delivery systems have been developed rapidly which show the ability to overcome the obstacles of traditional delivery systems. Daily development of biomedical and biomaterial sciences has brought more attention to the implantable delivery systems. As a result, these systems have found their position in the medical field since they were introduced. The advances in the polymeric science along with the other fields, make the production of a wide variety of implantable systems, possible. The influence of these systems in medical field could not be denied Here', the pharmaceutical applications which have been mostly focused on, are discussed. Since these systems have proven to be beneficial, researchers are trying to adjust their defects to the desired properties. Doing so, the path that implantable delivery systems have crossed so far should be studied, and that’s the aim of this review. In the present report, the advantages of these systems in chemotherapeutic, contraceptive, neuropsychology, pain management, peptide delivery, ocular delivery, cardiovascular, orthopedic, and dental fields have been evaluated.

Keywords:

• Pharmaceutical implants
• chemotherapeutical implants
• contraceptive implants
• ocular delivery
• peptide delivery
• pain management

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work supported by national institute for medical research development ministry of health and medical education, I.R.Iran Grant No: 962506.