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Journal of Chemotherapy Volume 30, 2018 - Issue 3
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Case Report

Treatment of a Klebsiella pneumoniae KPC cellulitis and gut decolonization with ceftazidime/avibactam in a migrant from Libya

Novella CarannanteFirst division of Infectious Diseases, Cotugno Hospital, AORN dei Colli, Naples, Italy
,
Carlo PallottoFirst division of Infectious Diseases, Cotugno Hospital, AORN dei Colli, Naples, Italy;Infectious Diseases Section, Department of Medicine, University of Perugia, Perugia, Italy
,
Mariano BernardoMicrobiology and Virology Unit, Cotugno Hospital, AORN dei Colli, Naples, Italy
,
Giovanni Di CaprioDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, Naples, Italy
&
Carlo TasciniFirst division of Infectious Diseases, Cotugno Hospital, AORN dei Colli, Naples, ItalyCorrespondence[email protected]
Pages 183-184 | Published online: 16 Jan 2018
 
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Abstract

KPC-producing Klebsiella pneumoniae (KPC-Kp) is nowadays a global concern. Ceftazidime/avibactam is the most promising novel antibiotic combination available at the moment. We describe the case of a migrant with no risk factors for an infection due to multidrug resistant bacteria. He suffered from a KPC-Kp cellulitis and was treated with a ceftazidime/avibactam-meropenem-fosfomycin combination that not only eradicated the infection but also decontaminated his gut. Ceftazidime/avibactam-based treatment can be useful also in decontamination procedures.

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