Mycochemical composition, bioactivities, and phylogenetic placement of three wild edible Russula species from Northern Odisha, India

Abstract

The study aimed at evaluating bioactivities, phytochemical constituents, and molecular phylogeny of three wild edible mushrooms Russula densifolia (Secr.) Gillet., Russula violeipes Quel., and Russula cyanoxantha (Schaeff.) Fr. The mushroom extracts showed 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, superoxide scavenging and metal chelating activities, α-glucosidase inhibition and α- amylase inhibition to different extents. The mushrooms extracts also showed an anti-inflammatory by inhibiting the denaturation of albumin. The studied mushrooms also displayed moderate antimicrobial properties with zones of inhibition ranging from 16.25 ± 0.42 to 25.50 ± 0.85 mm against seven human pathogens. Highest cytotoxic activity was exhibited by the ethanol extracts of R. violeipes with an IC₅₀ value of 56.66 µg/ml. Total phenol content was between 21.92–41.99 mg catechol/g extract and flavonoid content ranged from 2.53–7.52 mg quercetin/g extract. The Fourier-transform infrared spectroscopy (FTIR) analysis revealed the presence of different functional groups as mycoconstituents. The study indicated that wild edible mushrooms can be used as nutraceuticals/functional foods to promote health benefits.

Keywords:

• Mushroom
• antioxidant
• antidiabetic
• antibacterial
• mycoconstituents
• molecular phylogeny

Disclosure statement

No potential conflict of interest was reported by the authors.