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Summary
An historical and comparative analysis of congruent ultrastructural, genetical, restrictional and sequencing data has helped defining informational potential, and 100% reliability, of conventional transmission electron microscopy (CTEM) in probing the structure-related and function dependent evolutionary patterns of ct-DNA individual genetic monomers and multimeric genomic aggregates (nucleoids).
A number of methodological strategies have also been identified, which, at least in principle, should confer to the ultrastructural genome probing the semantic autonomy of a totally autarkic methodology testing genetic, functional and evolutionary versatility of the DNA genetic monomers and multimeric genomic aggregates of chloroplasts and other cytoplasmic organelles.