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ABSTRACT
Crohn's disease is known for its various complications and affection of systems other than the GI-tract, which altogether can seriously impair organ function or even lead to life-threatening conditions, especially in children. There are a variety of indices, created for evaluation of disease activity and severity, such as VCCD, CDEIS and CDAI. The case report is showing the practical use of such evaluation and the consequences drawn as well as the practical approach of interdisciplinary cooperation, stating diagnostics, drug therapy (following therapy protocols as well as the use of anti -TNF-α antibodies), monitoring nutritional status and providing both enteral and parenteral nutrition therapy, intensive care monitoring, surgery, as well as pre- and postoperative care. As shown in the case of a 13-year-old severely affected boy with a long history of the disease, manifesting a great lot of all possible complications, this approach results in reversal of the course of the disease or even decides its outcome.