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Journal of Neurovirology Volume 11, 2005 - Issue 1
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Original

Quantitative assessment of spasticity in human T-cell lymphotropic virus type I–associated myelopathy/tropical spastic paraparesis

JR Zunt Departments of Neurology, University of Washington School of Medicine, Seattle, Washington, USA; Departments of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
,
SM Montano Instituto de Ciencias Neurológicas, Lima, Perú
,
JOV Alarcón Universidad Nacional Mayor de San Marcos, Lima, Perú
,
WT Jr, Longstreth Departments of Neurology, University of Washington School of Medicine, Seattle, Washington, USA; Departments of Epidemiology, University of Washington School of Medicine, Seattle, Washington, USA
,
R Price, Departments of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington, USA
&
and KK Holmes Departments of Epidemiology, University of Washington School of Medicine, Seattle, Washington, USA; Departments of Medicine, University of Washington School of Medicine, Seattle, Washington, USA; Departments of Center for AIDS and STD, University of Washington School of Medicine, Seattle, Washington, USA
Pages 70-73 | Received 02 Oct 2003, Accepted 04 Oct 2004, Published online: 10 Jul 2009
 

Abstract

People with human T-cell lymphotropic virus type I–associated myelopathy/tropical spastic paraparesis (HAM/TSP) develop spasticity. The authors examined 34 patients with HAM/TSP in Perú using a device that measures tone in the gastroc-soleus-Achilles tendon unit and provides a quantitative spasticity assessment (QSA). Tone in the 34 patients was more than double that of women with asymptomatic HTLV-I infection. The device may help to track progression in HTLV-I infection.

This work was supported by NIH grants K23-AI01600, TW00679, and AI0714P, Fogarty International grant T22-TW00001, and the University of Washington Center for AIDS Research (CFAR) grant AI27757.

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