An unusual case of reversible mild cognitive impairment

ABSTRACT

Mild cognitive impairment (MCI) is cognitive dysfunction greater than expected for age and education in either a single cognitive domain or in multiple domains without impairment of activities of daily living. The present case report describes the case of an elderly male patient of 71 years who presented with MCI and was Venereal Disease Research Laboratory test reactive in serum. This was confirmed by Treponema pallidum Hemagglutination Assay. After a complete course of antibiotic therapy, his memory complaints disappeared completely. Though syphilis is termed as reversible dementia; to the best of our knowledge, this is the first case of MCI with reactive syphilis serology who responded to antimicrobial therapy.

KEYWORDS:

• Neurosyphilis
• mild cognitive impairment
• antibiotic therapy
• reversible dementia

Conflict of interest

None

Disclosure statement

No potential conflict of interest was reported by the authors.