Posterior cortical atrophy: a single case cognitive and radiological follow-up

ABSTRACT

Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome characterized by initial predominant visuoperceptual deficits followed by a progressive decline in other cognitive functions. This syndrome has not been as thoroughly described as other dementias, particularly from a neuropsychological evolution perspective with only a few studies describing the evolution of its cognitive progression. In this investigation we review the literature on this rare condition and we perform a 7-year neuropsychological and neuroradiological follow-up of a 64-year-old man with PCA. The subject’s deficits initially appeared in his visuoperceptual skills with later affectation appearing in language and other cognitive functions, this being coherent with the patient’s parieto-temporal atrophy evolution.

KEYWORDS:

• Posterior cortical atrophy
• dementia
• variant of Alzheimer’s disease
• cognitive and neuroradiological follow up

Acknowledgments

Study was supported by grants from CONICET and INECO Foundation.

Disclosure statement

The authors do not have any conflict of interest.

Additional information

Funding

This work was supported by the INECO Foundation; National Scientific and Technical Research Council (CONICET).