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Neurocase
Behavior, Cognition and Neuroscience
Volume 24, 2018 - Issue 5-6
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Reports

Neuro-Behçet’s disease presenting as an isolated progressive cognitive and behavioral syndrome

Dario SaracinoSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy
,
Lia AllegoricoSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy
,
Anna Maria BarbaruloSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy
,
Bianca PolloDivision of Neurology V – Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
,
Giorgio GiacconeDivision of Neurology V – Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
,
Alessandra D’AmicoDepartment of Advanced Biomedical Sciences, Neuroradiology, University “Federico II”, Naples, Italy
,
Ludovico D’IncertiNeuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
,
Orso BugianiDivision of Neurology V – Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
,
Giuseppe Di IorioSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy
,
Simone SampaoloSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy
&
Mariarosa Anna Beatrice MeloneSecond Division of Neurology, Center for Rare Neurological and Neuromuscular Diseases & Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy;Sbarro Institute for Cancer Research and Molecular Medicine, Department of Biology, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USACorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-7213-9277
ORCID Icon show all
Pages 238-241 | Received 23 Jan 2018, Accepted 30 Nov 2018, Published online: 25 Dec 2018
 
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ABSTRACT

Behçet’s disease is a chronic inflammatory disorder manifesting as a vasculitis that affects arteries and veins of any size. Up to 44% of cases may also present with neurological symptoms, thus defining Neuro-Behçet’s disease. We describe a case of Neuro-Behçet’s disease characterized by progressive behavioral and cognitive deterioration prevailing over other neurological symptoms, without evident systemic involvement.

Acknowledgments

We are grateful to doctors Guglielmo Capaldo, Clemente Dato, Luca Lombardi, Elisabetta Signoriello, Giacomo Lus, and Cinzia Coppola for their support in the clinical diagnosis of the patient, suggesting diagnostic procedures and contributing to data analysis.

Disclosure statement

No potential conflict of interest was reported by the authors.

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