ABSTRACT
Traumatic brain injury (TBI) is suggested to be a risk factor for the onset of Alzheimer’s disease (AD); however, the data remain controversial. This is the first report on cognitive decline in patients with TBI over 30 years post-injury. The medical significance/key learning points of this report are that (1) Functional Independence Measure (FIM) is useful in clinical settings, such as for higher brain dysfunction and dementia; (2) amyloid PET findings represent an essential biomarker for follow-up after TBI; and (3) cognitive decline can occur in patients with TBI more than 30 years post-injury.
Acknowledgments
We would like to thank Editage (www.editage.jp) for English language editing.
Data availability statement
The authors confirm that the data supporting the findings of this study are available within the article.
Disclosure statement
No potential conflict of interest was reported by the author.