Improved visuospatial neglect after tDCS and computer-assisted cognitive training in Posterior Cortical Atrophy: a single-case study

ABSTRACT

Visuospatial neglect (VN) frequently occurs in Posterior Cortical Atrophy (PCA) and requires specific rehabilitation. In this single-case study, we investigated the efficacy of a computer-assisted cognitive training (CCT) alone or coupled with multiple sessions of anodal transcranial direct-current stimulation (A-tDCS) over the right posterior parietal cortex in improving left VN symptoms in a patient with PCA. The digital ReMoVES platform was used for both VN assessment and training. We found a significant improvement after CCT combined with A-tDCS within the limits of a single-case, our results suggest, for the first time, the usefulness of this combined approach in a neurodegenerative disorder.

KEYWORDS:

• Visuospatial neglect
• posterior cortical atrophy
• tDCS
• posterior parietal cortex
• computer-assisted cognitive training

Acknowledgments

We would like to thank our patient for her participating in the study. We also would like to thank her husband for the assessments of IADL functions.

Disclosure statement

No potential conflict of interest was reported by the authors.