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Immunology

Alarmins and antimicrobial immunity

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Pages S146-S153 | Received 31 Jan 2008, Published online: 27 Feb 2009
 

Abstract

Alarmins are endogenous mediators capable of enhancing innate and adaptive immune response through induction of concomitant recruitment and activation of antigen-presenting cells. Here we provide a brief overview of various alarmins, highlight their critical roles in innate and adaptive antimicrobial immunity, and speculate on potential usage of alarmins in combating aspergillosis.

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