Abstract
We conducted two experiments with healthy subjects to investigate the possible relationships between Iowa Gambling Task (IGT) performance and executive functions as well as IGT performance and decision-making in a task with explicit rules, the Game of Dice Task (GDT). Results indicated that only the last trials of the IGT were correlated with executive functions and GDT performance. We suggest that the IGT taps into two mechanisms of decision-making: decisions under ambiguity in the first trials and decisions under risk in the latter trials. Results have impact on the interpretation of deficient IGT performance in patients with frontal lobe dysfunctions.
Acknowledgments
The work of M.B. on this paper was supported by a grant from the G.A.-Lienert-Foundation, Germany. The work of A.B. was supported by NIDA grants DA11779, DA12487, DA16708, and by NINDS grant NS19632.