Abstract
Individuals with aphasia face significant challenges in their lives. These challenges stem from the difficulties caused by impaired language function. Impairment in the ability to successfully communicate could be a significant source of stress to individuals with aphasia. The purpose of the current paper is to present a review of the literature on the neuropsychobiology of stress and aphasia, give a contemporary conceptualization of stress (both neurobiological and psychological), offer a framework and directions for future investigations in stress and aphasia, and finally suggest clinical implications for this line of inquiry.