De Ritis ratio and biochemical parameters in COVID-19 patients

Abstract

Background

The study aimed to examine some biochemical test parameters and De Ritis ratio in COVID-19 patients, considering age and gender.

Method

The study was performed on patients with real-time polymerase chain reaction and computed tomography lung diagnosis. The relationship between lactate dehydrogenase, creatine kinase (CK), creatine kinase-MB, alanine aminotransferase, aspartate aminotransferase and De Ritis ratio were analysed in the first blood samples of the patients. The difference between gender was also compared with the independent sample t-test. Alpha value was accepted <0.05.

Results

The De Ritis was significantly higher in females (p = .040). The De Ritis ratio was associated with CK in both gender. There was no significant difference in the biochemical parameters according to gender.

Conclusion

The De Ritis ratio appears to be a parameter that can be used in COVID-19 patients. However, more detailed and comprehensive studies including the symptoms of patients are needed.

Keywords:

• COVID-19
• De Ritis ratio
• AST
• ALT
• CK
• CK-MB
• LDH

Disclosure statement

The authors report no declarations of interest.